Sage Therapeutics, Inc.

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Investigation Details

Before the market opened on April 17, 2024, Sage issued a press release “announc[ing] . . . topline results from PRECEDENT, a double-blind, placebo-controlled Phase 2 study of the investigational oral medicine dalzanemdor (SAGE-718) in people with mild cognitive impairment (MCI) in Parkinson’s Disease (PD).” Sage stated that “[t]he PRECEDENT Study did not meet its primary endpoint of demonstrating statistically significant difference from baseline in participants treated with once-daily dalzanemdor versus placebo”.

On this news, Sage’s stock price fell $3.06 per share, or 19.58%, to close at $12.57 per share on April 17, 2024.